About Protein Wnt-11
Protein Wnt-11 (WNT11) is a protein
from Homo sapiens identified by UniProt accession
O96014, 354 residues long.
MolForge cross-references it against 0 known binders and
191 disease associations.
Target properties
| Protein name | Protein Wnt-11 |
|---|
| UniProt accession | O96014 |
|---|
| Gene | WNT11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 354 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (191)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.44
- PR interval · score 0.42
- platelet count · score 0.40
- hemoglobin A1 measurement · score 0.32
- neurodegenerative disease · score 0.28
- Eczematoid dermatitis · score 0.25
- protein measurement · score 0.23
- platelet crit · score 0.19
- Osteoporosis · score 0.19
- osteoporosis · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O96014-F1 | alphafold | PREDICTED | 90.21 | — |
Amino-acid sequence (354 residues)
MRARPQVCEA LLFALALQTG VCYGIKWLAL SKTPSALALN QTQHCKQLEG LVSAQVQLCR SNLELMHTVV HAAREVMKAC RRAFADMRWN CSSIELAPNY LLDLERGTRE SAFVYALSAA AISHAIARAC TSGDLPGCSC GPVPGEPPGP GNRWGGCADN LSYGLLMGAK FSDAPMKVKK TGSQANKLMR LHNSEVGRQA LRASLEMKCK CHGVSGSCSI RTCWKGLQEL QDVAADLKTR YLSATKVVHR PMGTRKHLVP KDLDIRPVKD SELVYLQSSP DFCMKNEKVG SHGTQDRQCN KTSNGSDSCD LMCCGRGYNP YTDRVVERCH CKYHWCCYVT CRRCERTVER YVCK
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