Beta-1,3-galactosyltransferase 4 (B3GALT4)

About Beta-1,3-galactosyltransferase 4

Beta-1,3-galactosyltransferase 4 (B3GALT4) is a protein from Homo sapiens identified by UniProt accession O96024, 378 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Beta-1,3-galactosyltransferase 4
UniProt accession	O96024
Gene	B3GALT4
Organism	Homo sapiens
Length	378 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.22
platelet crit · score 0.10
platelet count · score 0.09
neoplasm · score 0.06
neuroblastoma · score 0.04
smoking status measurement · score 0.03
self reported educational attainment · score 0.03
gait measurement · score 0.03
triple-negative breast cancer · score 0.03
inflammatory bowel disease · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O96024-F1	alphafold	PREDICTED	84.95	—

Amino-acid sequence (378 residues)

MQLRLFRRLL LAALLLVIVW TLFGPSGLGE ELLSLSLASL LPAPASPGPP LALPRLLIPN QEACSGPGAP PFLLILVCTA PENLNQRNAI RASWGGLREA RGLRVQTLFL LGEPNAQHPV WGSQGSDLAS ESAAQGDILQ AAFQDSYRNL TLKTLSGLNW AEKHCPMARY VLKTDDDVYV NVPELVSELV LRGGRWGQWE RSTEPQREAE QEGGQVLHSE EVPLLYLGRV HWRVNPSRTP GGRHRVSEEQ WPHTWGPFPP YASGTGYVLS ASAVQLILKV ASRAPLLPLE DVFVGVSARR GGLAPTQCVK LAGATHYPLD RCCYGKFLLT SHRLDPWKMQ EAWKLVGGSD GERTAPFCSW FQGVLGILRC RAIAWLQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards