About Cytochrome b5
Cytochrome b5 (CYB5A) is a protein
from Homo sapiens identified by UniProt accession
P00167, 134 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | Cytochrome b5 |
|---|
| UniProt accession | P00167 |
|---|
| Gene | CYB5A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 134 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.47
- hereditary methemoglobinemia · score 0.43
- sex hormone-binding globulin measurement · score 0.39
- methemoglobinemia · score 0.37
- 46,XY disorder of sex development due to isolated 17,20 lyase deficiency · score 0.37
- bilirubin measurement · score 0.33
- creatinine measurement · score 0.27
- platelet count · score 0.23
- hepatocellular carcinoma · score 0.09
- PHF-tau measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P00167-F1 | alphafold | PREDICTED | 80.31 | — |
Amino-acid sequence (134 residues)
MAEQSDEAVK YYTLEEIQKH NHSKSTWLIL HHKVYDLTKF LEEHPGGEEV LREQAGGDAT ENFEDVGHST DAREMSKTFI IGELHPDDRP KLNKPPETLI TTIDSSSSWW TNWVIPAISA VAVALMYRLY MAED
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