Alpha-lactalbumin (LALBA)

About Alpha-lactalbumin

Alpha-lactalbumin (LALBA) is a protein from Homo sapiens identified by UniProt accession P00709, 142 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein name	Alpha-lactalbumin
UniProt accession	P00709
Gene	LALBA
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (68)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin concentration · score 0.07
breast carcinoma · score 0.06
neoplasm · score 0.04
pancreatic adenocarcinoma · score 0.04
carcinoma of liver and intrahepatic biliary tract · score 0.02
polycystic ovary syndrome · score 0.01
breast cancer · score 0.01
cancer · score 0.01
urinary bladder carcinoma · score 0.01
breast ductal carcinoma in situ · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P00709-F1	alphafold	PREDICTED	91.68	—

Amino-acid sequence (142 residues)

MRFFVPLFLV GILFPAILAK QFTKCELSQL LKDIDGYGGI ALPELICTMF HTSGYDTQAI VENNESTEYG LFQISNKLWC KSSQVPQSRN ICDISCDKFL DDDITDDIMC AKKILDIKGI DYWLAHKALC TEKLEQWLCE KL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards