About Protein c-Fos
Protein c-Fos (FOS) is a protein
from Homo sapiens identified by UniProt accession
P01100, 380 residues long.
MolForge cross-references it against 0 known binders and
1,110 disease associations.
Target properties
| Protein name | Protein c-Fos |
|---|
| UniProt accession | P01100 |
|---|
| Gene | FOS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 380 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1110)
Diseases linked to this target (Open Targets).
- congenital generalized lipodystrophy · score 0.37
- inflammatory bowel disease · score 0.32
- glioblastoma multiforme · score 0.30
- Crohn's disease · score 0.30
- heel bone mineral density · score 0.27
- head and neck squamous cell carcinoma · score 0.27
- neurodegenerative disease · score 0.27
- ovarian cancer · score 0.26
- alkaline phosphatase measurement · score 0.26
- endometrial cancer · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01100-F1 | alphafold | PREDICTED | 57.20 | — |
Amino-acid sequence (380 residues)
MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNAQDFC TDLAVSSANF IPTVTAISTS PDLQWLVQPA LVSSVAPSQT RAPHPFGVPA PSAGAYSRAG VVKTMTGGRA QSIGRRGKVE QLSPEEEEKR RIRRERNKMA AAKCRNRRRE LTDTLQAETD QLEDEKSALQ TEIANLLKEK EKLEFILAAH RPACKIPDDL GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL
Explore Protein c-Fos with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets