About Vasopressin-neurophysin 2-copeptin
Vasopressin-neurophysin 2-copeptin (AVP) is a protein
from Homo sapiens identified by UniProt accession
P01185, 164 residues long.
MolForge cross-references it against 0 known binders and
1,003 disease associations.
Target properties
| Protein name | Vasopressin-neurophysin 2-copeptin |
|---|
| UniProt accession | P01185 |
|---|
| Gene | AVP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 164 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1003)
Diseases linked to this target (Open Targets).
- Hereditary central diabetes insipidus · score 0.77
- neurohypophyseal diabetes insipidus · score 0.77
- diabetes insipidus · score 0.27
- thyroid gland adenocarcinoma · score 0.25
- breast adenocarcinoma · score 0.25
- cutaneous melanoma · score 0.24
- genetic disorder · score 0.18
- head and neck squamous cell carcinoma · score 0.17
- Stroke · score 0.11
- stroke · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01185-F1 | alphafold | PREDICTED | 79.46 | — |
Amino-acid sequence (164 residues)
MPDTMLPACF LGLLAFSSAC YFQNCPRGGK RAMSDLELRQ CLPCGPGGKG RCFGPSICCA DELGCFVGTA EALRCQEENY LPSPCQSGQK ACGSGGRCAA FGVCCNDESC VTEPECREGF HRRARASDRS NATQLDGPAG ALLLRLVQLA GAPEPFEPAQ PDAY
Explore Vasopressin-neurophysin 2-copeptin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets