About Proenkephalin-B
Proenkephalin-B (PDYN) is a protein
from Homo sapiens identified by UniProt accession
P01213, 254 residues long.
MolForge cross-references it against 0 known binders and
251 disease associations.
Target properties
| Protein name | Proenkephalin-B |
|---|
| UniProt accession | P01213 |
|---|
| Gene | PDYN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 254 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (251)
Diseases linked to this target (Open Targets).
- spinocerebellar ataxia type 23 · score 0.77
- mean platelet volume · score 0.37
- platelet crit · score 0.35
- bone density · score 0.32
- urate measurement · score 0.32
- aortic root size · score 0.31
- glioblastoma multiforme · score 0.26
- neurodegenerative disease · score 0.26
- ovarian cancer · score 0.25
- basophil count · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01213-F1 | alphafold | PREDICTED | 58.69 | — |
Amino-acid sequence (254 residues)
MAWQGLVLAA CLLMFPSTTA DCLSRCSLCA VKTQDGPKPI NPLICSLQCQ AALLPSEEWE RCQSFLSFFT PSTLGLNDKE DLGSKSVGEG PYSELAKLSG SFLKELEKSK FLPSISTKEN TLSKSLEEKL RGLSDGFREG AESELMRDAQ LNDGAMETGT LYLAEEDPKE QVKRYGGFLR KYPKRSSEVA GEGDGDSMGH EDLYKRYGGF LRRIRPKLKW DNQKRYGGFL RRQFKVVTRS QEDPNAYSGE LFDA
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