About Follitropin subunit beta
Follitropin subunit beta (FSHB) is a protein
from Homo sapiens identified by UniProt accession
P01225, 129 residues long.
MolForge cross-references it against 0 known binders and
313 disease associations.
Target properties
| Protein name | Follitropin subunit beta |
|---|
| UniProt accession | P01225 |
|---|
| Gene | FSHB |
|---|
| Organism | Homo sapiens |
|---|
| Length | 129 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (313)
Diseases linked to this target (Open Targets).
- hypogonadotropic hypogonadism 24 without anosmia · score 0.73
- Isolated follicle stimulating hormone deficiency · score 0.69
- testosterone measurement · score 0.35
- neurodegenerative disease · score 0.34
- menstrual cycle measurement · score 0.32
- polycystic ovary syndrome · score 0.26
- age at menopause · score 0.25
- heel bone mineral density · score 0.25
- lung adenocarcinoma · score 0.23
- ovarian cancer · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01225-F1 | alphafold | PREDICTED | 89.79 | — |
Amino-acid sequence (129 residues)
MKTLQFFFLF CCWKAICCNS CELTNITIAI EKEECRFCIS INTTWCAGYC YTRDLVYKDP ARPKIQKTCT FKELVYETVR VPGCAHHADS LYTYPVATQC HCGKCDSDST DCTVRGLGPS YCSFGEMKE
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