About Prolactin
Prolactin (PRL) is a protein
from Homo sapiens identified by UniProt accession
P01236, 227 residues long.
MolForge cross-references it against 0 known binders and
1,339 disease associations.
Target properties
| Protein name | Prolactin |
|---|
| UniProt accession | P01236 |
|---|
| Gene | PRL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1339)
Diseases linked to this target (Open Targets).
- AL amyloidosis · score 0.46
- hypertension · score 0.41
- basophil count · score 0.41
- neutrophil count · score 0.39
- leukocyte count · score 0.39
- systolic blood pressure · score 0.39
- lymphocyte count · score 0.37
- monocyte count · score 0.37
- myeloid white cell count · score 0.36
- cardiovascular disease · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01236-F1 | alphafold | PREDICTED | 85.56 | — |
Amino-acid sequence (227 residues)
MNIKGSPWKG SLLLLLVSNL LLCQSVAPLP ICPGGAARCQ VTLRDLFDRA VVLSHYIHNL SSEMFSEFDK RYTHGRGFIT KAINSCHTSS LATPEDKEQA QQMNQKDFLS LIVSILRSWN EPLYHLVTEV RGMQEAPEAI LSKAVEIEEQ TKRLLEGMEL IVSQVHPETK ENEIYPVWSG LPSLQMADEE SRLSAYYNLL HCLRRDSHKI DNYLKLLKCR IIHNNNC
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