About Somatotropin
Somatotropin (GH1) is a protein
from Homo sapiens identified by UniProt accession
P01241, 217 residues long.
MolForge cross-references it against 0 known binders and
1,472 disease associations.
Target properties
| Protein name | Somatotropin |
|---|
| UniProt accession | P01241 |
|---|
| Gene | GH1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 217 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1472)
Diseases linked to this target (Open Targets).
- Non-acquired isolated growth hormone deficiency · score 0.74
- isolated growth hormone deficiency type II · score 0.73
- isolated growth hormone deficiency type IB · score 0.70
- short stature due to growth hormone qualitative anomaly · score 0.68
- isolated growth hormone deficiency type IA · score 0.60
- lean body mass · score 0.58
- IGF-1 measurement · score 0.58
- body height · score 0.57
- body weights and measures · score 0.44
- whole body water mass · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01241-F1 | alphafold | PREDICTED | 79.30 | — |
Amino-acid sequence (217 residues)
MATGSRTSLL LAFGLLCLPW LQEGSAFPTI PLSRLFDNAM LRAHRLHQLA FDTYQEFEEA YIPKEQKYSF LQNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF
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