About Growth hormone variant
Growth hormone variant (GH2) is a protein
from Homo sapiens identified by UniProt accession
P01242, 217 residues long.
MolForge cross-references it against 0 known binders and
112 disease associations.
Target properties
| Protein name | Growth hormone variant |
|---|
| UniProt accession | P01242 |
|---|
| Gene | GH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 217 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (112)
Diseases linked to this target (Open Targets).
- body height · score 0.28
- BMI-adjusted hip circumference · score 0.18
- PR interval · score 0.16
- BMI-adjusted waist circumference · score 0.12
- gestational diabetes · score 0.09
- serum alanine aminotransferase measurement · score 0.07
- hemoglobin measurement · score 0.07
- hematocrit · score 0.07
- brain volume measurement · score 0.06
- neuroimaging measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01242-F1 | alphafold | PREDICTED | 80.32 | — |
Amino-acid sequence (217 residues)
MAAGSRTSLL LAFGLLCLSW LQEGSAFPTI PLSRLFDNAM LRARRLYQLA YDTYQEFEEA YILKEQKYSF LQNPQTSLCF SESIPTPSNR VKTQQKSNLE LLRISLLLIQ SWLEPVQLLR SVFANSLVYG ASDSNVYRHL KDLEEGIQTL MWRLEDGSPR TGQIFNQSYS KFDTKSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF
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