Calcitonin (CALCA)

About Calcitonin

Calcitonin (CALCA) is a protein from Homo sapiens identified by UniProt accession P01258, 141 residues long. MolForge cross-references it against 0 known binders and 1,152 disease associations.

Target properties

Protein name	Calcitonin
UniProt accession	P01258
Gene	CALCA
Organism	Homo sapiens
Length	141 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1152)

Diseases linked to this target (Open Targets).

migraine disorder · score 0.66
AL amyloidosis · score 0.46
pain · score 0.38
trigeminal neuralgia · score 0.37
neuralgia · score 0.37
neurodegenerative disease · score 0.26
glioblastoma multiforme · score 0.18
vitamin D measurement · score 0.15
infection · score 0.12
infect · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01258-F1	alphafold	PREDICTED	63.91	—

Amino-acid sequence (141 residues)

MGFQKFSPFL ALSILVLLQA GSLHAAPFRS ALESSPADPA TLSEDEARLL LAALVQDYVQ MKASELEQEQ EREGSSLDSP RSKRCGNLST CMLGTYTQDF NKFHTFPQTA IGVGAPGKKR DMSSDLERDH RPHVSMPQNA N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards