Somatoliberin (GHRH)

About Somatoliberin

Somatoliberin (GHRH) is a protein from Homo sapiens identified by UniProt accession P01286, 108 residues long. MolForge cross-references it against 0 known binders and 370 disease associations.

Target properties

Protein name	Somatoliberin
UniProt accession	P01286
Gene	GHRH
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (370)

Diseases linked to this target (Open Targets).

body height · score 0.57
IGF-1 measurement · score 0.57
lean body mass · score 0.49
body weights and measures · score 0.45
sitting height measurement · score 0.43
whole body water mass · score 0.37
forced expiratory volume · score 0.34
base metabolic rate measurement · score 0.22
anthropometric measurement · score 0.21
ovarian cancer · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01286-F1	alphafold	PREDICTED	77.74	—

Amino-acid sequence (108 residues)

MPLWVFFFVI LTLSNSSHCS PPPPLTLRMR RYADAIFTNS YRKVLGQLSA RKLLQDIMSR QQGESNQERG ARARLGRQVD SMWAEQKQME LESILVALLQ KHSRNSQG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards