Pro-neuropeptide Y (NPY)

About Pro-neuropeptide Y

Pro-neuropeptide Y (NPY) is a protein from Homo sapiens identified by UniProt accession P01303, 97 residues long. MolForge cross-references it against 0 known binders and 684 disease associations.

Target properties

Protein name	Pro-neuropeptide Y
UniProt accession	P01303
Gene	NPY
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (684)

Diseases linked to this target (Open Targets).

body mass index · score 0.43
PHF-tau measurement · score 0.39
cognitive function measurement · score 0.31
body height · score 0.30
neurodegenerative disease · score 0.28
self reported educational attainment · score 0.24
chronotype measurement · score 0.23
verbal-numerical reasoning measurement · score 0.22
forced expiratory volume · score 0.22
vital capacity · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01303-F1	alphafold	PREDICTED	75.65	—

Amino-acid sequence (97 residues)

MLGNKRLGLS GLTLALSLLV CLGALAEAYP SKPDNPGEDA PAEDMARYYS ALRHYINLIT RQRYGKRSSP ETLISDLLMR ESTENVPRTR LEDPAMW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards