Interferon alpha-2 (IFNA2)

About Interferon alpha-2

Interferon alpha-2 (IFNA2) is a protein from Homo sapiens identified by UniProt accession P01563, 188 residues long. MolForge cross-references it against 0 known binders and 593 disease associations.

Target properties

Protein name	Interferon alpha-2
UniProt accession	P01563
Gene	IFNA2
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (593)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
neoplasm · score 0.11
systemic lupus erythematosus · score 0.11
Systemic lupus erythematosus · score 0.11
COVID-19 · score 0.10
infection · score 0.09
infect · score 0.09
psoriasis · score 0.09
chronic hepatitis B virus infection · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01563-F1	alphafold	PREDICTED	85.08	—

Amino-acid sequence (188 residues)

MALTFALLVA LLVLSCKSSC SVGCDLPQTH SLGSRRTLML LAQMRRISLF SCLKDRHDFG FPQEEFGNQF QKAETIPVLH EMIQQIFNLF STKDSSAAWD ETLLDKFYTE LYQQLNDLEA CVIQGVGVTE TPLMKEDSIL AVRKYFQRIT LYLKEKKYSP CAWEVVRAEI MRSFSLSTNL QESLRSKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards