About Interferon alpha-21
Interferon alpha-21 (IFNA21) is a protein
from Homo sapiens identified by UniProt accession
P01568, 189 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Interferon alpha-21 |
|---|
| UniProt accession | P01568 |
|---|
| Gene | IFNA21 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 189 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.19
- CINCA syndrome · score 0.18
- breast adenocarcinoma · score 0.18
- glioblastoma multiforme · score 0.15
- susceptibility to shingles measurement · score 0.11
- systemic lupus erythematosus · score 0.11
- coronary artery disease · score 0.04
- dermatomyositis · score 0.04
- psoriasis · score 0.04
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01568-F1 | alphafold | PREDICTED | 84.98 | — |
Amino-acid sequence (189 residues)
MALSFSLLMA VLVLSYKSIC SLGCDLPQTH SLGNRRALIL LAQMGRISPF SCLKDRHDFG FPQEEFDGNQ FQKAQAISVL HEMIQQTFNL FSTKDSSATW EQSLLEKFST ELNQQLNDLE ACVIQEVGVE ETPLMNVDSI LAVKKYFQRI TLYLTEKKYS PCAWEVVRAE IMRSFSLSKI FQERLRRKE
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