Interferon alpha-5 (IFNA5)

About Interferon alpha-5

Interferon alpha-5 (IFNA5) is a protein from Homo sapiens identified by UniProt accession P01569, 189 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Interferon alpha-5
UniProt accession	P01569
Gene	IFNA5
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

systemic lupus erythematosus · score 0.20
ovarian cancer · score 0.18
lung adenocarcinoma · score 0.18
drug use measurement · score 0.10
lupus nephritis · score 0.05
psoriasis · score 0.04
dermatomyositis · score 0.04
family history of lung cancer · score 0.02
squamous cell lung carcinoma · score 0.02
infection · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01569-F1	alphafold	PREDICTED	87.53	—

Amino-acid sequence (189 residues)

MALPFVLLMA LVVLNCKSIC SLGCDLPQTH SLSNRRTLMI MAQMGRISPF SCLKDRHDFG FPQEEFDGNQ FQKAQAISVL HEMIQQTFNL FSTKDSSATW DETLLDKFYT ELYQQLNDLE ACMMQEVGVE DTPLMNVDSI LTVRKYFQRI TLYLTEKKYS PCAWEVVRAE IMRSFSLSAN LQERLRRKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards