Interferon alpha-14 (IFNA14)

About Interferon alpha-14

Interferon alpha-14 (IFNA14) is a protein from Homo sapiens identified by UniProt accession P01570, 189 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Interferon alpha-14
UniProt accession	P01570
Gene	IFNA14
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
systemic lupus erythematosus · score 0.11
brain volume measurement · score 0.10
drug use measurement · score 0.10
dermatomyositis · score 0.04
psoriasis · score 0.04
body height · score 0.02
childhood leukemia · score 0.02
HIV infection · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01570-F1	alphafold	PREDICTED	84.66	—

Amino-acid sequence (189 residues)

MALPFALMMA LVVLSCKSSC SLGCNLSQTH SLNNRRTLML MAQMRRISPF SCLKDRHDFE FPQEEFDGNQ FQKAQAISVL HEMMQQTFNL FSTKNSSAAW DETLLEKFYI ELFQQMNDLE ACVIQEVGVE ETPLMNEDSI LAVKKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSLSFSTN LQKRLRRKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards