Interferon beta (IFNB1)

About Interferon beta

Interferon beta (IFNB1) is a protein from Homo sapiens identified by UniProt accession P01574, 187 residues long. MolForge cross-references it against 0 known binders and 933 disease associations.

Target properties

Protein name	Interferon beta
UniProt accession	P01574
Gene	IFNB1
Organism	Homo sapiens
Length	187 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (933)

Diseases linked to this target (Open Targets).

low grade glioma · score 0.26
myositis · score 0.26
breast adenocarcinoma · score 0.26
glioblastoma multiforme · score 0.26
ovarian cancer · score 0.25
lung adenocarcinoma · score 0.23
esophageal cancer · score 0.19
CINCA syndrome · score 0.18
neurodegenerative disease · score 0.16
neoplasm · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01574-F1	alphafold	PREDICTED	89.38	—

Amino-acid sequence (187 residues)

MTNKCLLQIA LLLCFSTTAL SMSYNLLGFL QRSSNFQCQK LLWQLNGRLE YCLKDRMNFD IPEEIKQLQQ FQKEDAALTI YEMLQNIFAI FRQDSSSTGW NETIVENLLA NVYHQINHLK TVLEEKLEKE DFTRGKLMSS LHLKRYYGRI LHYLKAKEYS HCAWTIVRVE ILRNFYFINR LTGYLRN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards