Interferon gamma (IFNG)

About Interferon gamma

Interferon gamma (IFNG) is a protein from Homo sapiens identified by UniProt accession P01579, 166 residues long. MolForge cross-references it against 0 known binders and 2,497 disease associations.

Target properties

Protein name	Interferon gamma
UniProt accession	P01579
Gene	IFNG
Organism	Homo sapiens
Length	166 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (4)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (2497)

Diseases linked to this target (Open Targets).

Primary hemophagocytic lymphohistiocytosis · score 0.49
immunodeficiency 69 · score 0.46
lymphocyte count · score 0.43
platelet count · score 0.42
Aplastic anemia · score 0.42
ulcerative colitis · score 0.41
immune system disease · score 0.39
HIV-1 infection · score 0.38
idiopathic aplastic anemia · score 0.38
tuberous sclerosis · score 0.38

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01579-F1	alphafold	PREDICTED	85.32	—

Amino-acid sequence (166 residues)

MKYTSYILAF QLCIVLGSLG CYCQDPYVKE AENLKKYFNA GHSDVADNGT LFLGILKNWK EESDRKIMQS QIVSFYFKLF KNFKDDQSIQ KSVETIKEDM NVKFFNSNKK KRDDFEKLTN YSVTDLNVQR KAIHELIQVM AELSPAAKTG KRKRSQMLFR GRRASQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards