About Erythropoietin
Erythropoietin (EPO) is a protein
from Homo sapiens identified by UniProt accession
P01588, 193 residues long.
MolForge cross-references it against 0 known binders and
1,148 disease associations.
Target properties
| Protein name | Erythropoietin |
|---|
| UniProt accession | P01588 |
|---|
| Gene | EPO |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1148)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.55
- hematocrit · score 0.55
- erythrocyte count · score 0.55
- mean corpuscular hemoglobin concentration · score 0.53
- primary familial polycythemia due to EPO receptor mutation · score 0.51
- Blackfan-Diamond anemia · score 0.47
- autosomal dominant secondary polycythemia · score 0.37
- red blood cell density measurement · score 0.31
- platelet count · score 0.30
- bilirubin measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P01588-F1 | alphafold | PREDICTED | 86.39 | — |
Amino-acid sequence (193 residues)
MGVHECPAWL WLLLSLLSLP LGLPVLGAPP RLICDSRVLE RYLLEAKEAE NITTGCAEHC SLNENITVPD TKVNFYAWKR MEVGQQAVEV WQGLALLSEA VLRGQALLVN SSQPWEPLQL HVDKAVSGLR SLTTLLRALG AQKEAISPPD AASAAPLRTI TADTFRKLFR VYSNFLRGKL KLYTGEACRT GDR
Explore Erythropoietin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets