Immunoglobulin kappa variable 1D-16 (IGKV1D-16)

About Immunoglobulin kappa variable 1D-16

Immunoglobulin kappa variable 1D-16 (IGKV1D-16) is a protein from Homo sapiens identified by UniProt accession P01601, 117 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 1D-16
UniProt accession	P01601
Gene	IGKV1D-16
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.04
Crohn's disease · score 0.02
ulcerative colitis · score 0.01
lung adenocarcinoma · score 0.01
non-small cell lung carcinoma · score 0.01
cutaneous lupus erythematosus · score 0.01
hepatocellular carcinoma · score 0.01
MALT lymphoma · score 0.01
colorectal cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01601-F1	alphafold	PREDICTED	89.28	—

Amino-acid sequence (117 residues)

MDMRVLAQLL GLLLLCFPGA RCDIQMTQSP SSLSASVGDR VTITCRASQG ISSWLAWYQQ KPEKAPKSLI YAASSLQSGV PSRFSGSGSG TDFTLTISSL QPEDFATYYC QQYNSYP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards