Immunoglobulin kappa variable 1D-12 (IGKV1D-12)

About Immunoglobulin kappa variable 1D-12

Immunoglobulin kappa variable 1D-12 (IGKV1D-12) is a protein from Homo sapiens identified by UniProt accession P01611, 117 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 1D-12
UniProt accession	P01611
Gene	IGKV1D-12
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
neoplasm · score 0.07
Barrett's esophagus · score 0.02
cancer · score 0.01
sarcoma · score 0.01
ovarian carcinoma · score 0.01
non-small cell lung carcinoma · score 0.01
Crohn's disease · score 0.01
multiple myeloma · score 0.01
mesothelioma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01611-F1	alphafold	PREDICTED	90.87	—

Amino-acid sequence (117 residues)

MDMMVPAQLL GLLLLWFPGS RCDIQMTQSP SSVSASVGDR VTITCRASQG ISSWLAWYQQ KPGKAPKLLI YAASSLQSGV PSRFSGSGSG TDFTLTISSL QPEDFATYYC QQANSFP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards