Immunoglobulin kappa variable 2D-28 (IGKV2D-28)

About Immunoglobulin kappa variable 2D-28

Immunoglobulin kappa variable 2D-28 (IGKV2D-28) is a protein from Homo sapiens identified by UniProt accession P01615, 120 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 2D-28
UniProt accession	P01615
Gene	IGKV2D-28
Organism	Homo sapiens
Length	120 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (106)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
cancer · score 0.03
neoplasm · score 0.02
ulcerative colitis · score 0.02
infect · score 0.02
infection · score 0.02
Crohn's disease · score 0.02
triple-negative breast cancer · score 0.02
melanoma · score 0.01
nuclear cataract · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01615-F1	alphafold	PREDICTED	91.01	—

Amino-acid sequence (120 residues)

MRLPAQLLGL LMLWVSGSSG DIVMTQSPLS LPVTPGEPAS ISCRSSQSLL HSNGYNYLDW YLQKPGQSPQ LLIYLGSNRA SGVPDRFSGS GSGTDFTLKI SRVEAEDVGV YYCMQALQTP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards