Immunoglobulin kappa variable 3-20 (IGKV3-20)

About Immunoglobulin kappa variable 3-20

Immunoglobulin kappa variable 3-20 (IGKV3-20) is a protein from Homo sapiens identified by UniProt accession P01619, 116 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 3-20
UniProt accession	P01619
Gene	IGKV3-20
Organism	Homo sapiens
Length	116 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
squamous cell carcinoma · score 0.06
osteosarcoma · score 0.05
rheumatoid arthritis · score 0.04
sebaceous of Jadassohn nevus · score 0.04
esophageal adenocarcinoma · score 0.04
central nervous system cancer · score 0.04
Acute hepatic failure · score 0.03
Crohn's disease · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01619-F1	alphafold	PREDICTED	90.00	—

Amino-acid sequence (116 residues)

METPAQLLFL LLLWLPDTTG EIVLTQSPGT LSLSPGERAT LSCRASQSVS SSYLAWYQQK PGQAPRLLIY GASSRATGIP DRFSGSGSGT DFTLTISRLE PEDFAVYYCQ QYGSSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards