Immunoglobulin kappa variable 3-15 (IGKV3-15)

About Immunoglobulin kappa variable 3-15

Immunoglobulin kappa variable 3-15 (IGKV3-15) is a protein from Homo sapiens identified by UniProt accession P01624, 115 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 3-15
UniProt accession	P01624
Gene	IGKV3-15
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
sebaceous of Jadassohn nevus · score 0.06
squamous cell carcinoma · score 0.04
Crohn's disease · score 0.03
cutaneous lupus erythematosus · score 0.02
idiopathic pulmonary fibrosis · score 0.02
Barrett's esophagus · score 0.02
ulcerative colitis · score 0.02
central nervous system cancer · score 0.02
Lyme disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01624-F1	alphafold	PREDICTED	89.78	—

Amino-acid sequence (115 residues)

MEAPAQLLFL LLLWLPDTTG EIVMTQSPAT LSVSPGERAT LSCRASQSVS SNLAWYQQKP GQAPRLLIYG ASTRATGIPA RFSGSGSGTE FTLTISSLQS EDFAVYYCQQ YNNWP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards