Immunoglobulin lambda variable 1-44 (IGLV1-44)

About Immunoglobulin lambda variable 1-44

Immunoglobulin lambda variable 1-44 (IGLV1-44) is a protein from Homo sapiens identified by UniProt accession P01699, 117 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 1-44
UniProt accession	P01699
Gene	IGLV1-44
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
squamous cell carcinoma · score 0.05
esophageal adenocarcinoma · score 0.04
Crohn's disease · score 0.03
sebaceous of Jadassohn nevus · score 0.02
central nervous system cancer · score 0.02
cutaneous lupus erythematosus · score 0.01
ulcerative colitis · score 0.01
idiopathic pulmonary fibrosis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01699-F1	alphafold	PREDICTED	89.64	—

Amino-acid sequence (117 residues)

MASFPLLLTL LTHCAGSWAQ SVLTQPPSAS GTPGQRVTIS CSGSSSNIGS NTVNWYQQLP GTAPKLLIYS NNQRPSGVPD RFSGSKSGTS ASLAISGLQS EDEADYYCAA WDDSLNG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards