Immunoglobulin lambda variable 1-47 (IGLV1-47)

About Immunoglobulin lambda variable 1-47

Immunoglobulin lambda variable 1-47 (IGLV1-47) is a protein from Homo sapiens identified by UniProt accession P01700, 117 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 1-47
UniProt accession	P01700
Gene	IGLV1-47
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
squamous cell carcinoma · score 0.05
osteosarcoma · score 0.05
Barrett's esophagus · score 0.04
Acute hepatic failure · score 0.04
sebaceous of Jadassohn nevus · score 0.03
esophageal adenocarcinoma · score 0.03
central nervous system cancer · score 0.03
Crohn's disease · score 0.03
periodontitis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01700-F1	alphafold	PREDICTED	89.18	—

Amino-acid sequence (117 residues)

MAGFPLLLTL LTHCAGSWAQ SVLTQPPSAS GTPGQRVTIS CSGSSSNIGS NYVYWYQQLP GTAPKLLIYS NNQRPSGVPD RFSGSKSGTS ASLAISGLRS EDEADYYCAA WDDSLSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards