Immunoglobulin lambda variable 1-51 (IGLV1-51)

About Immunoglobulin lambda variable 1-51

Immunoglobulin lambda variable 1-51 (IGLV1-51) is a protein from Homo sapiens identified by UniProt accession P01701, 117 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 1-51
UniProt accession	P01701
Gene	IGLV1-51
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.05
esophageal adenocarcinoma · score 0.04
Crohn's disease · score 0.03
ulcerative colitis · score 0.02
idiopathic pulmonary fibrosis · score 0.01
Leishmaniasis · score 0.01
systemic lupus erythematosus · score 0.00
hepatocellular carcinoma · score 0.00
Lyme disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01701-F1	alphafold	PREDICTED	89.40	—

Amino-acid sequence (117 residues)

MTCSPLLLTL LIHCTGSWAQ SVLTQPPSVS AAPGQKVTIS CSGSSSNIGN NYVSWYQQLP GTAPKLLIYD NNKRPSGIPD RFSGSKSGTS ATLGITGLQT GDEADYYCGT WDSSLSA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards