Immunoglobulin lambda variable 2-11 (IGLV2-11)

About Immunoglobulin lambda variable 2-11

Immunoglobulin lambda variable 2-11 (IGLV2-11) is a protein from Homo sapiens identified by UniProt accession P01706, 119 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 2-11
UniProt accession	P01706
Gene	IGLV2-11
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
esophageal adenocarcinoma · score 0.04
squamous cell carcinoma · score 0.04
Crohn's disease · score 0.03
sebaceous of Jadassohn nevus · score 0.02
colorectal cancer · score 0.02
central nervous system cancer · score 0.02
idiopathic pulmonary fibrosis · score 0.01
Leishmaniasis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01706-F1	alphafold	PREDICTED	86.57	—

Amino-acid sequence (119 residues)

MAWALLLLSL LTQGTGSWAQ SALTQPRSVS GSPGQSVTIS CTGTSSDVGG YNYVSWYQQH PGKAPKLMIY DVSKRPSGVP DRFSGSKSGN TASLTISGLQ AEDEADYYCC SYAGSYTFH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards