Immunoglobulin lambda variable 3-19 (IGLV3-19)

About Immunoglobulin lambda variable 3-19

Immunoglobulin lambda variable 3-19 (IGLV3-19) is a protein from Homo sapiens identified by UniProt accession P01714, 112 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 3-19
UniProt accession	P01714
Gene	IGLV3-19
Organism	Homo sapiens
Length	112 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.07
squamous cell carcinoma · score 0.06
esophageal adenocarcinoma · score 0.04
osteosarcoma · score 0.04
Crohn's disease · score 0.02
central nervous system cancer · score 0.02
ulcerative colitis · score 0.02
periodontitis · score 0.02
idiopathic pulmonary fibrosis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01714-F1	alphafold	PREDICTED	89.34	—

Amino-acid sequence (112 residues)

MAWTPLWLTL LTLCIGSVVS SELTQDPAVS VALGQTVRIT CQGDSLRSYY ASWYQQKPGQ APVLVIYGKN NRPSGIPDRF SGSSSGNTAS LTITGAQAED EADYYCNSRD SS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards