Immunoglobulin lambda variable 3-25 (IGLV3-25)

About Immunoglobulin lambda variable 3-25

Immunoglobulin lambda variable 3-25 (IGLV3-25) is a protein from Homo sapiens identified by UniProt accession P01717, 112 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 3-25
UniProt accession	P01717
Gene	IGLV3-25
Organism	Homo sapiens
Length	112 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
esophageal adenocarcinoma · score 0.05
osteosarcoma · score 0.04
sebaceous of Jadassohn nevus · score 0.03
ulcerative colitis · score 0.02
periodontitis · score 0.02
cutaneous lupus erythematosus · score 0.01
central nervous system cancer · score 0.01
Crohn's disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01717-F1	alphafold	PREDICTED	89.50	—

Amino-acid sequence (112 residues)

MAWIPLLLPL LTLCTGSEAS YELTQPPSVS VSPGQTARIT CSGDALPKQY AYWYQQKPGQ APVLVIYKDS ERPSGIPERF SGSSSGTTVT LTISGVQAED EADYYCQSAD SS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards