Immunoglobulin lambda variable 3-27 (IGLV3-27)

About Immunoglobulin lambda variable 3-27

Immunoglobulin lambda variable 3-27 (IGLV3-27) is a protein from Homo sapiens identified by UniProt accession P01718, 113 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 3-27
UniProt accession	P01718
Gene	IGLV3-27
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.01
ulcerative colitis · score 0.01
cutaneous lupus erythematosus · score 0.01
systemic lupus erythematosus · score 0.01
colorectal cancer · score 0.00
Leishmaniasis · score 0.00
idiopathic pulmonary fibrosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01718-F1	alphafold	PREDICTED	89.36	—

Amino-acid sequence (113 residues)

MAWIPLLLPL LILCTVSVAS YELTQPSSVS VSPGQTARIT CSGDVLAKKY ARWFQQKPGQ APVLVIYKDS ERPSGIPERF SGSSSGTTVT LTISGAQVED EADYYCYSAA DNN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards