Immunoglobulin lambda variable 6-57 (IGLV6-57)

About Immunoglobulin lambda variable 6-57

Immunoglobulin lambda variable 6-57 (IGLV6-57) is a protein from Homo sapiens identified by UniProt accession P01721, 117 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 6-57
UniProt accession	P01721
Gene	IGLV6-57
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
esophageal adenocarcinoma · score 0.04
sebaceous of Jadassohn nevus · score 0.04
squamous cell carcinoma · score 0.02
ulcerative colitis · score 0.02
Crohn's disease · score 0.02
idiopathic pulmonary fibrosis · score 0.01
lung adenocarcinoma · score 0.01
non-small cell lung carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01721-F1	alphafold	PREDICTED	89.96	—

Amino-acid sequence (117 residues)

MAWAPLLLTL LAHCTGSWAN FMLTQPHSVS ESPGKTVTIS CTGSSGSIAS NYVQWYQQRP GSAPTTVIYE DNQRPSGVPD RFSGSIDSSS NSASLTISGL KTEDEADYYC QSYDSSN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards