T-cell surface glycoprotein CD8 alpha chain (CD8A)

About T-cell surface glycoprotein CD8 alpha chain

T-cell surface glycoprotein CD8 alpha chain (CD8A) is a protein from Homo sapiens identified by UniProt accession P01732, 235 residues long. MolForge cross-references it against 0 known binders and 2,284 disease associations.

Target properties

Protein name	T-cell surface glycoprotein CD8 alpha chain
UniProt accession	P01732
Gene	CD8A
Organism	Homo sapiens
Length	235 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01732-F1	alphafold	PREDICTED	78.21	—

Amino-acid sequence (235 residues)

MALPVTALLL PLALLLHAAR PSQFRVSPLD RTWNLGETVE LKCQVLLSNP TSGCSWLFQP RGAAASPTFL LYLSQNKPKA AEGLDTQRFS GKRLGDTFVL TLSDFRRENE GYYFCSALSN SIMYFSHFVP VFLPAKPTTT PAPRPPTPAP TIASQPLSLR PEACRPAAGG AVHTRGLDFA CDIYIWAPLA GTCGVLLLSL VITLYCNHRN RRRVCKCPRP VVKSGDKPSL SARYV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards