T cell receptor alpha variable 8-4 (TRAV8-4)

About T cell receptor alpha variable 8-4

T cell receptor alpha variable 8-4 (TRAV8-4) is a protein from Homo sapiens identified by UniProt accession P01737, 113 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

Target properties

Protein name	T cell receptor alpha variable 8-4
UniProt accession	P01737
Gene	TRAV8-4
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

colorectal adenocarcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01737-F1	alphafold	PREDICTED	90.62	—

Amino-acid sequence (113 residues)

MLLLLVPVLE VIFTLGGTRA QSVTQLGSHV SVSEGALVLL RCNYSSSVPP YLFWYVQYPN QGLQLLLKYT SAATLVKGIN GFEAEFKKSE TSFHLTKPSA HMSDAAEYFC AVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards