Immunoglobulin heavy variable 3-23 (IGHV3-23)

About Immunoglobulin heavy variable 3-23

Immunoglobulin heavy variable 3-23 (IGHV3-23) is a protein from Homo sapiens identified by UniProt accession P01764, 117 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Immunoglobulin heavy variable 3-23
UniProt accession	P01764
Gene	IGHV3-23
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.06
squamous cell carcinoma · score 0.06
esophageal adenocarcinoma · score 0.04
central nervous system cancer · score 0.04
Acute hepatic failure · score 0.03
actinic keratosis · score 0.02
chronic lymphocytic leukemia · score 0.02
myotonic dystrophy · score 0.02
Crohn's disease · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P01764-F1	alphafold	PREDICTED	91.00	—

Amino-acid sequence (117 residues)

MEFGLSWLFL VAILKGVQCE VQLVESGGGL VQPGGSLRLS CAASGFTFSS YAMSWVRQAP GKGLEWVSAI SGSGGSTYYA DSVKGRFTIS RDNSKNTLYL QMNSLRAEDT AVYYCAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards