About Hemoglobin subunit delta
Hemoglobin subunit delta (HBD) is a protein
from Homo sapiens identified by UniProt accession
P02042, 147 residues long.
MolForge cross-references it against 0 known binders and
220 disease associations.
Target properties
| Protein name | Hemoglobin subunit delta |
|---|
| UniProt accession | P02042 |
|---|
| Gene | HBD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 147 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (220)
Diseases linked to this target (Open Targets).
- delta-beta-thalassemia · score 0.62
- Hereditary persistence of fetal hemoglobin - beta-thalassemia · score 0.37
- Alpha-thalassemia · score 0.35
- alpha thalassemia spectrum · score 0.34
- Abnormal hemoglobin · score 0.34
- Persistence of hemoglobin F · score 0.34
- anemia · score 0.34
- Reduced beta/alpha synthesis ratio · score 0.34
- glucocorticoid-remediable aldosteronism · score 0.27
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02042-F1 | alphafold | PREDICTED | 96.95 | — |
Amino-acid sequence (147 residues)
MVHLTPEEKT AVNALWGKVN VDAVGGEALG RLLVVYPWTQ RFFESFGDLS SPDAVMGNPK VKAHGKKVLG AFSDGLAHLD NLKGTFSQLS ELHCDKLHVD PENFRLLGNV LVCVLARNFG KEFTPQMQAA YQKVVAGVAN ALAHKYH
Explore Hemoglobin subunit delta with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets