Myoglobin (MB)

About Myoglobin

Myoglobin (MB) is a protein from Homo sapiens identified by UniProt accession P02144, 154 residues long. MolForge cross-references it against 0 known binders and 557 disease associations.

Target properties

Protein name	Myoglobin
UniProt accession	P02144
Gene	MB
Organism	Homo sapiens
Length	154 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (557)

Diseases linked to this target (Open Targets).

triglyceride measurement · score 0.32
high density lipoprotein cholesterol measurement · score 0.26
acute kidney failure · score 0.11
neoplasm · score 0.10
diabetic nephropathy · score 0.09
myocarditis · score 0.09
acute myocardial infarction · score 0.07
sex hormone-binding globulin measurement · score 0.07
hypertrophic cardiomyopathy · score 0.06
dilated cardiomyopathy · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02144-F1	alphafold	PREDICTED	97.18	—

Amino-acid sequence (154 residues)

MGLSDGEWQL VLNVWGKVEA DIPGHGQEVL IRLFKGHPET LEKFDKFKHL KSEDEMKASE DLKKHGATVL TALGGILKKK GHHEAEIKPL AQSHATKHKI PVKYLEFISE CIIQVLQSKH PGDFGADAQG AMNKALELFR KDMASNYKEL GFQG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards