About Myelin basic protein
Myelin basic protein (MBP) is a protein
from Homo sapiens identified by UniProt accession
P02686, 304 residues long.
MolForge cross-references it against 0 known binders and
739 disease associations.
Target properties
| Protein name | Myelin basic protein |
|---|
| UniProt accession | P02686 |
|---|
| Gene | MBP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 304 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (739)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.43
- insomnia · score 0.32
- total blood protein measurement · score 0.32
- poisoning · score 0.27
- brain volume measurement · score 0.26
- neuroimaging measurement · score 0.26
- facial asymmetry measurement · score 0.12
- experimental autoimmune encephalomyelitis · score 0.11
- myeloid sarcoma · score 0.11
- dehydroepiandrosterone sulphate measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02686-F1 | alphafold | PREDICTED | 54.13 | — |
Amino-acid sequence (304 residues)
MGNHAGKREL NAEKASTNSE TNRGESEKKR NLGELSRTTS EDNEVFGEAD ANQNNGTSSQ DTAVTDSKRT ADPKNAWQDA HPADPGSRPH LIRLFSRDAP GREDNTFKDR PSESDELQTI QEDSAATSES LDVMASQKRP SQRHGSKYLA TASTMDHARH GFLPRHRDTG ILDSIGRFFG GDRGAPKRGS GKDSHHPART AHYGSLPQKS HGRTQDENPV VHFFKNIVTP RTPPPSQGKG RGLSLSRFSW GAEGQRPGFG YGGRASDYKS AHKGFKGVDA QGTLSKIFKL GGRDSRSGSP MARR
Explore Myelin basic protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets