About Myelin P2 protein
Myelin P2 protein (PMP2) is a protein
from Homo sapiens identified by UniProt accession
P02689, 132 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Myelin P2 protein |
|---|
| UniProt accession | P02689 |
|---|
| Gene | PMP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 132 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- Charcot-Marie-Tooth disease type 1G · score 0.73
- peripheral neuropathy · score 0.33
- genetic disorder · score 0.32
- hereditary neuropathy with liability to pressure palsies · score 0.04
- Charcot-Marie-Tooth disease type 2B2 · score 0.03
- Barrett's esophagus · score 0.03
- medulloblastoma · score 0.03
- atypical teratoid rhabdoid tumor · score 0.02
- Charcot-Marie-Tooth disease · score 0.02
- high density lipoprotein cholesterol measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02689-F1 | alphafold | PREDICTED | 96.39 | — |
Amino-acid sequence (132 residues)
MSNKFLGTWK LVSSENFDDY MKALGVGLAT RKLGNLAKPT VIISKKGDII TIRTESTFKN TEISFKLGQE FEETTADNRK TKSIVTLQRG SLNQVQRWDG KETTIKRKLV NGKMVAECKM KGVVCTRIYE KV
Explore Myelin P2 protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets