Glycophorin-A (GYPA)

About Glycophorin-A

Glycophorin-A (GYPA) is a protein from Homo sapiens identified by UniProt accession P02724, 150 residues long. MolForge cross-references it against 0 known binders and 282 disease associations.

Target properties

Protein name	Glycophorin-A
UniProt accession	P02724
Gene	GYPA
Organism	Homo sapiens
Length	150 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (282)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.55
reticulocyte count · score 0.54
mean reticulocyte volume · score 0.49
monocyte count · score 0.48
HbA1c measurement · score 0.47
mean corpuscular hemoglobin · score 0.46
leukocyte count · score 0.46
mean corpuscular hemoglobin concentration · score 0.46
erythrocyte count · score 0.45
reticulocyte measurement · score 0.44

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02724-F1	alphafold	PREDICTED	59.40	—

Amino-acid sequence (150 residues)

MYGKIIFVLL LSEIVSISAL STTEVAMHTS TSSSVTKSYI SSQTNDTHKR DTYAATPRAH EVSEISVRTV YPPEEETGER VQLAHHFSEP EITLIIFGVM AGVIGTILLI SYGIRRLIKK SPSDVKPLPS PDTDVPLSSV EIENPETSDQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards