C-reactive protein (CRP)

About C-reactive protein

C-reactive protein (CRP) is a protein from Homo sapiens identified by UniProt accession P02741, 224 residues long. MolForge cross-references it against 0 known binders and 2,160 disease associations.

Target properties

Protein name	C-reactive protein
UniProt accession	P02741
Gene	CRP
Organism	Homo sapiens
Length	224 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02741-F1	alphafold	PREDICTED	94.14	—

Amino-acid sequence (224 residues)

MEKLLCFLVL TSLSHAFGQT DMSRKAFVFP KESDTSYVSL KAPLTKPLKA FTVCLHFYTE LSSTRGYSIF SYATKRQDNE ILIFWSKDIG YSFTVGGSEI LFEVPEVTVA PVHICTSWES ASGIVEFWVD GKPRVRKSLK KGYTVGAEAS IILGQEQDSF GGNFEGSQSL VGDIGNVNMW DFVLSPDEIN TIYLGGPFSP NVLNWRALKY EVQGEVFTKP QLWP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards