Protein AMBP (AMBP)

About Protein AMBP

Protein AMBP (AMBP) is a protein from Homo sapiens identified by UniProt accession P02760, 352 residues long. MolForge cross-references it against 0 known binders and 282 disease associations.

Target properties

Protein name	Protein AMBP
UniProt accession	P02760
Gene	AMBP
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (282)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.36
lifestyle measurement · score 0.33
cutaneous melanoma · score 0.18
squamous cell lung carcinoma · score 0.18
endometrial cancer · score 0.16
head and neck squamous cell carcinoma · score 0.15
chronotype measurement · score 0.13
balding measurement · score 0.13
arterial stiffness measurement · score 0.13
neutrophil count · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02760-F1	alphafold	PREDICTED	81.48	—

Amino-acid sequence (352 residues)

MRSLGALLLL LSACLAVSAG PVPTPPDNIQ VQENFNISRI YGKWYNLAIG STCPWLKKIM DRMTVSTLVL GEGATEAEIS MTSTRWRKGV CEETSGAYEK TDTDGKFLYH KSKWNITMES YVVHTNYDEY AIFLTKKFSR HHGPTITAKL YGRAPQLRET LLQDFRVVAQ GVGIPEDSIF TMADRGECVP GEQEPEPILI PRVRRAVLPQ EEEGSGGGQL VTEVTKKEDS CQLGYSAGPC MGMTSRYFYN GTSMACETFQ YGGCMGNGNN FVTEKECLQT CRTVAACNLP IVRGPCRAFI QLWAFDAVKG KCVLFPYGGC QGNGNKFYSE KECREYCGVP GDGDEELLRF SN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards