About Platelet factor 4
Platelet factor 4 (PF4) is a protein
from Homo sapiens identified by UniProt accession
P02776, 101 residues long.
MolForge cross-references it against 0 known binders and
542 disease associations.
Target properties
| Protein name | Platelet factor 4 |
|---|
| UniProt accession | P02776 |
|---|
| Gene | PF4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 101 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (542)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.47
- serum metabolite measurement · score 0.35
- interleukin 7 measurement · score 0.28
- CD5 measurement · score 0.28
- very low density lipoprotein cholesterol measurement · score 0.28
- bone morphogenetic protein 10 measurement · score 0.28
- breast adenocarcinoma · score 0.27
- coronary artery calcification · score 0.25
- ephrin type-B receptor 2 measurement · score 0.25
- squamous cell lung carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02776-F1 | alphafold | PREDICTED | 75.03 | — |
Amino-acid sequence (101 residues)
MSSAAGFCAS RPGLLFLGLL LLPLVVAFAS AEAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S
Explore Platelet factor 4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets