C-X-C motif chemokine 10 (CXCL10)

About C-X-C motif chemokine 10

C-X-C motif chemokine 10 (CXCL10) is a protein from Homo sapiens identified by UniProt accession P02778, 98 residues long. MolForge cross-references it against 0 known binders and 1,219 disease associations.

Target properties

Protein name	C-X-C motif chemokine 10
UniProt accession	P02778
Gene	CXCL10
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1219)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
C-X-C motif chemokine 11 measurement · score 0.15
blood protein measurement · score 0.14
neoplasm · score 0.12
protein measurement · score 0.12
fetal genotype effect measurement · score 0.12
ulcerative colitis · score 0.12
infection · score 0.11
infect · score 0.11
tropical spastic paraparesis · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02778-F1	alphafold	PREDICTED	89.53	—

Amino-acid sequence (98 residues)

MNQTAILICC LIFLTLSGIQ GVPLSRTVRC TCISISNQPV NPRSLEKLEI IPASQFCPRV EIIATMKKKG EKRCLNPESK AIKNLLKAVS KERSKRSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards