About Hemopexin
Hemopexin (HPX) is a protein
from Homo sapiens identified by UniProt accession
P02790, 462 residues long.
MolForge cross-references it against 0 known binders and
375 disease associations.
Target properties
| Protein name | Hemopexin |
|---|
| UniProt accession | P02790 |
|---|
| Gene | HPX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 462 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (375)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.21
- cutaneous melanoma · score 0.18
- squamous cell lung carcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.15
- glioblastoma multiforme · score 0.11
- neoplasm · score 0.09
- acute kidney failure · score 0.08
- malaria · score 0.08
- experimental autoimmune encephalomyelitis · score 0.08
- Spinal cord injury · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02790-F1 | alphafold | PREDICTED | 87.58 | — |
Amino-acid sequence (462 residues)
MARVLGAPVA LGLWSLCWSL AIATPLPPTS AHGNVAEGET KPDPDVTERC SDGWSFDATT LDDNGTMLFF KGEFVWKSHK WDRELISERW KNFPSPVDAA FRQGHNSVFL IKGDKVWVYP PEKKEKGYPK LLQDEFPGIP SPLDAAVECH RGECQAEGVL FFQGDREWFW DLATGTMKER SWPAVGNCSS ALRWLGRYYC FQGNQFLRFD PVRGEVPPRY PRDVRDYFMP CPGRGHGHRN GTGHGNSTHH GPEYMRCSPH LVLSALTSDN HGATYAFSGT HYWRLDTSRD GWHSWPIAHQ WPQGPSAVDA AFSWEEKLYL VQGTQVYVFL TKGGYTLVSG YPKRLEKEVG TPHGIILDSV DAAFICPGSS RLHIMAGRRL WWLDLKSGAQ ATWTELPWPH EKVDGALCME KSLGPNSCSA NGPGLYLIHG PNLYCYSDVE KLNAAKALPQ PQNVTSLLGC TH
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