About Ferritin light chain
Ferritin light chain (FTL) is a protein
from Homo sapiens identified by UniProt accession
P02792, 175 residues long.
MolForge cross-references it against 0 known binders and
256 disease associations.
Target properties
| Protein name | Ferritin light chain |
|---|
| UniProt accession | P02792 |
|---|
| Gene | FTL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 175 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (256)
Diseases linked to this target (Open Targets).
- hereditary hyperferritinemia with congenital cataracts · score 0.79
- neuroferritinopathy · score 0.76
- L-ferritin deficiency · score 0.62
- genetic disorder · score 0.40
- movement disorder · score 0.37
- Genetic hyperferritinemia without iron overload · score 0.37
- head and neck squamous cell carcinoma · score 0.20
- lung adenocarcinoma · score 0.20
- hepatocellular carcinoma · score 0.10
- glioblastoma multiforme · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P02792-F1 | alphafold | PREDICTED | 96.66 | — |
Amino-acid sequence (175 residues)
MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLFERL TLKHD
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