Salivary acidic proline-rich phosphoprotein 1/2 (PRH1)

About Salivary acidic proline-rich phosphoprotein 1/2

Salivary acidic proline-rich phosphoprotein 1/2 (PRH1) is a protein from Homo sapiens identified by UniProt accession P02810, 166 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Salivary acidic proline-rich phosphoprotein 1/2
UniProt accession	P02810
Gene	PRH1
Organism	Homo sapiens
Length	166 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.07
sebaceous of Jadassohn nevus · score 0.05
sensory perception of bitter taste · score 0.04
actinic keratosis · score 0.04
tea consumption measurement · score 0.03
coffee consumption measurement · score 0.02
breast carcinoma · score 0.02
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P02810-F1	alphafold	PREDICTED	67.18	—

Amino-acid sequence (166 residues)

MLLILLSVAL LAFSSAQDLD EDVSQEDVPL VISDGGDSEQ FIDEERQGPP LGGQQSQPSA GDGNQNDGPQ QGPPQQGGQQ QQGPPPPQGK PQGPPQQGGH PPPPQGRPQG PPQQGGHPRP PRGRPQGPPQ QGGHQQGPPP PPPGKPQGPP PQGGRPQGPP QGQSPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards