About Angiogenin
Angiogenin (ANG) is a protein
from Homo sapiens identified by UniProt accession
P03950, 147 residues long.
MolForge cross-references it against 0 known binders and
489 disease associations.
Target properties
| Protein name | Angiogenin |
| UniProt accession | P03950 |
| Gene | ANG |
| Organism | Homo sapiens |
| Length | 147 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (489)
Diseases linked to this target (Open Targets).
- amyotrophic lateral sclerosis · score 0.67
- blood protein measurement · score 0.39
- Amyotrophic lateral sclerosis · score 0.38
- angiogenin measurement · score 0.34
- frontotemporal dementia · score 0.26
- genetic disorder · score 0.18
- protein measurement · score 0.17
- familial amyotrophic lateral sclerosis · score 0.12
- frontotemporal dementia with motor neuron disease · score 0.12
- axial length measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P03950-F1 | alphafold | PREDICTED | 89.84 | — |
Amino-acid sequence (147 residues)
MVMGLGVLLL VFVLGLGLTP PTLAQDNSRY THFLTQHYDA KPQGRDDRYC ESIMRRRGLT SPCKDINTFI HGNKRSIKAI CENKNGNPHR ENLRISKSSF QVTTCKLHGG SPWPPCQYRA TAGFRNVVVA CENGLPVHLD QSIFRRP
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