Angiogenin (ANG)

Homo sapiens — UniProt P03950

Gene: ANGHomo sapiensSwissProt reviewed

About Angiogenin

Angiogenin (ANG) is a protein from Homo sapiens identified by UniProt accession P03950, 147 residues long. MolForge cross-references it against 0 known binders and 489 disease associations.

Target properties

Protein nameAngiogenin
UniProt accessionP03950
GeneANG
OrganismHomo sapiens
Length147 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (489)

Diseases linked to this target (Open Targets).

  • amyotrophic lateral sclerosis · score 0.67
  • blood protein measurement · score 0.39
  • Amyotrophic lateral sclerosis · score 0.38
  • angiogenin measurement · score 0.34
  • frontotemporal dementia · score 0.26
  • genetic disorder · score 0.18
  • protein measurement · score 0.17
  • familial amyotrophic lateral sclerosis · score 0.12
  • frontotemporal dementia with motor neuron disease · score 0.12
  • axial length measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P03950-F1alphafoldPREDICTED89.84—

Amino-acid sequence (147 residues)

MVMGLGVLLL VFVLGLGLTP PTLAQDNSRY THFLTQHYDA KPQGRDDRYC ESIMRRRGLT SPCKDINTFI HGNKRSIKAI CENKNGNPHR ENLRISKSSF QVTTCKLHGG SPWPPCQYRA TAGFRNVVVA CENGLPVHLD QSIFRRP

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Quick facts

UniProtP03950
GeneANG
OrganismHomo sapiens
Length147
Binders0
Diseases489
View on UniProt